Ionizing radiation regulates long non-coding RNAs in human peripheral blood mononuclear cells
نویسندگان
چکیده
منابع مشابه
Ionizing radiation regulates long non-coding RNAs in human peripheral blood mononuclear cells
Long non-coding RNAs (lncRNAs) are non-protein coding transcripts that modulate mRNA and microRNA (miRNA) expression, thereby controlling multiple cellular processes, including transcriptional regulation of gene expression, cell differentiation and apoptosis. Ionizing radiation (IR), a strong cellular stressor, is known to influence gene expression of irradiated cells, mainly by activation of o...
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Protein-coding genes account for only a small fraction of the human genome and most of the genomic sequences are transcriptionally silent, but recent observations indicate significant functional elements, including non-coding protein transcripts in the human genome. Long non-coding RNAs (lncRNAs) have been defined as transcripts of >200 nucleotides without protein-coding capacity that perform t...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2016
ISSN: 0449-3060,1349-9157
DOI: 10.1093/jrr/rrw111